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Regulatory Genomics of Preeclampsia-Specific Risk Variants Highlights Immune and Endothelial Mechanisms

2026-05-29

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Preeclampsia (PE) is a complex hypertensive disorder of pregnancy characterized by endothelial dysfunction, immune dysregulation, and systemic vascular injury. Multiple genome-wide association studies (GWAS) have revealed genetic signals shared with hypertension and blood pressure traits, potentially obscuring biological mechanisms that are more specific to PE pathogenesis....

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Literature Corpus work
29f4b659-ed9a-55f3-bd61-667dd05c5b53
DOI
10.64898/2026.05.26.728031
Open publication

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Regulatory Genomics of Preeclampsia-Specific Risk Variants Highlights Immune and Endothelial MechanismsDOI 10.64898/2026.05.26.728031
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