Article
Genetic Correlation and Causal Inference Between Female Fat Distribution and Preeclampsia: An Integrative Genomic Study.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 30 Jun 2026
Wang Man, Huang Li, Zhang Danfeng, Yang Fengmei, Wu Lihua, Gao Bo
Abstract excerpt
Preeclampsia (PE) is a major cause of maternal and perinatal morbidity. Because abnormal fat distribution is closely related to metabolic dysfunction, vascular injury, and hypertensive disorders during pregnancy, clarifying its genetic relationship with PE may improve our understanding of adverse pregnancy outcomes. Here, we investigated the shared genetic architecture between PE and waist-hip ratio adjusted for...
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