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Molecular subtyping of hypertensive disorders of pregnancy

8 Apr 2025

Abstract excerpt

Hypertensive disorders of pregnancy (HDP), including preeclampsia, affect 1 in 6 pregnancies, are major contributors to maternal morbidity and mortality, yet lack precision medicine strategies. Analyzing transcriptomic data from a prospectively-collected diverse cohort (n = 9102), this study reveals distinct RNA subtypes in maternal blood, reclassifying clinical HDP phenotypes like early/late-onset preeclampsia....

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PMID: 40199872
DOI: 10.1038/s41467-025-58157-y

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