Article

Varicella-zoster virus CNS vasculitis and RNA polymerase III gene mutation in identical twins

2018-01-08

Abstract excerpt

Deficiency in the cytosolic DNA sensor RNA Polymerase III was recently described in children with severe varicella zoster infection in the CNS or lungs. Here we describe a pair of monozygotic female twins, who both experienced severe recurrent CNS vasculitis caused by VZV reactivation. The clinical presentation and findings included recurrent episodes of headache, dizziness, and neurological deficits, cerebrospina...

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Literature Corpus work: 29e7e41a-181a-5019-af20-b0702296c5f2
DOI: 10.1101/244848

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