RNA Polymerase III Suppresses Varicella Zoster Virus in Human Neurons.

Abstract excerpt

INTRODUCTION: Varicella zoster virus (VZV) is a ubiquitous human alphaherpesvirus, latently present in the majority of the population. Knowledge on the molecular mechanisms underlying VZV reactivation from peripheral ganglia is incomplete, as is our understanding of why only a small number of individuals develop life-threatening complications following reactivation. Previously, we have reported a pathogenic...

Topics

Join the communities discussing this publication.

• Cell Line
• Herpesvirus 3, Human
• Mutation
• Neurons
• RNA Polymerase III