Article

gdGSE: a novel pathway enrichment evaluation algorithm based on discretization of gene expression values

2024-11-18

Abstract excerpt

<title>Abstract</title> <p>We proposed gdGSE, a novel gene set enrichment scoring method. Unlike the established methods, gdGSE evaluates gene set enrichment levels based on discretized gene expression values whereby to overcome the discrepancy of data distribution. This algorithm consists of two steps: the first step is to binarize gene expression matrix, and the second step is to convert the binarized gene expr...

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Literature Corpus work: 297240bb-8eec-55fc-8505-b021eceb6186
DOI: 10.21203/rs.3.rs-5391380/v1

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