Article
IGSA: Individual Gene Sets Analysis, including Enrichment and Clustering.
PloS one - 1 Jan 2016
Wu Lingxiang, Chen Xiujie, Zhang Denan, Zhang Wubing, Liu Lei, Ma Hongzhe, Yang Jingbo, Xie Hongbo, Liu Bo, Jin Qing
Abstract excerpt
Analysis of gene sets has been widely applied in various high-throughput biological studies. One weakness in the traditional methods is that they neglect the heterogeneity of genes expressions in samples which may lead to the omission of some specific and important gene sets. It is also difficult for them to reflect the severities of disease and provide expression profiles of gene sets for individuals. We...
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