Article

Prevalence of cancer susceptibility variants in patients with multiple Lynch syndrome related cancers

2021-02-23

Abstract excerpt

<h4>Background</h4> Along with early onset cancers, multiple primary cancers (MPCs) are likely resulting from increased genetic susceptibility; however, the associated predisposition genes or prevalence of the pathogenic variants genes in MPC patients are often unknown. <h4>Methods</h4> We screened 71 patients with MPC of the stomach, colorectal, and endometrium, sequencing 65 cancer predisposition genes. A subset...

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Literature Corpus work: 296f0800-06de-526c-9af2-d709dffaa7f3
DOI: 10.1101/2021.02.22.21250719

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