Article

Human sperm chromatin forms spatially restricted nucleosome domains consistent with programmed nucleosome positioning

2018-11-28

Abstract excerpt

In human sperm, a fraction of its chromatin retains nucleosomes that are positioned on specific sequences containing genes and regulatory units essential for embryonic development. This nucleosome positioning (NP) feature provides an inherited epigenetic mark for sperm. However, it is not known whether there is a structural constraint for these nucleosomes and, if so, how they are localized in a three-dimensional...

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Literature Corpus work: 296ba2c4-d8a4-55a9-83fe-3d8297ec526b
DOI: 10.1101/481028

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