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Article

Human Sperm Morphology as a Marker of Its Nuclear Quality and Epigenetic Pattern

30 May 2022

Abstract excerpt

Background: Human sperm chromatin condensation is a sum of epigenetic events that allows for the near-complete replacement of histones with protamines. Under high-magnification microscopy, nuclear vacuoles have been described as thumbprints with poor chromatin condensation. The objective of this study is to examine whether vacuolated spermatozoa carry specific epigenetic marks, which may influence embryo...

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PMID: 35681482
DOI: 10.3390/cells11111788

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