Back to search

Article

Attenuated APC contributes to FGF12 expression and EC progression with an integrated multi-omics analysis

2023-02-17

Abstract excerpt

<h4>Background: </h4> Endometrial cancer (EC) is one of the most common gynecological cancer worldwide. The high-order chromatin structure plays an important role in gene expression regulation. In our previous research, the chromatin remodeling-related gene APC (adenomatous polyposis coli gene) is frequently mutated in endometrial cancer. In this study, we aimed to figure out the role of the APC gene in the chroma...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
294fc032-d44b-5af3-8618-d053958fd783
DOI
10.21203/rs.3.rs-2590191/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Attenuated APC contributes to FGF12 expression and EC progression with an integrated multi-omics analysisDOI 10.21203/rs.3.rs-2590191/v1
Exploration of a Novel Biomarker in Endometrial CarcinomaSemantic proximity
Genomic Comparison of Endometrioid Endometrial Carcinoma and Its Precancerous Lesions in Chinese Patients by High-Depth Next Generation SequencingSemantic proximity
From Genes to Clinical Practice: Exploring the Genomic Underpinnings of Endometrial CancerSemantic proximity
Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes.Semantic proximity
MECOM and the PRDM gene family in uterine endometrial cancer: bioinformatics and experimental insights into pathogenesis and therapeutic potentialsSemantic proximity
From Genes to Clinical Practice: Exploring the Genomic Underpinnings of Endometrial CancerSemantic proximity
Unveiling DNA methylation: early diagnosis, risk assessment, and therapy for endometrial cancerSemantic proximity
Role of DNA Methylation and Epigenetic Silencing of HAND2 in Endometrial Cancer DevelopmentSemantic proximity
Identification of DNA methylation associated gene signatures in endometrial cancer via integrated analysis of DNA methylation and gene expression systematicallySemantic proximity
Genomic landscape of endometrial polyps.Semantic proximity
Enhancer plasticity in endometrial tumorigenesis demarcates non-coding somatic mutations and 3D-genome alterations boosting the oncogenic driver ESR1Semantic proximity
An Update on the Potential Roles of E2F Family Members in Colorectal CancerSemantic proximity
Select a neighboring publication to make it the new centre.