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From Genes to Clinical Practice: Exploring the Genomic Underpinnings of Endometrial Cancer

2024-10-18

Abstract excerpt

Endometrial cancer (EC), a prevalent gynecological malignancy, presents significant challenges due to its genetic complexity and heterogeneity. The genomic landscape of EC is underpinned by genetic alterations, such as mutations in PTEN, PIK3CA, and ARID1A, and chromosomal abnormalities. The identification of molecular subtypes—POLE-ultramutated, microsatellite instability (MSI), copy-number low, and copy-nu...

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Literature Corpus work
721f0972-9cea-5aa7-bbe4-f8aa5dce2627
DOI
10.20944/preprints202410.1326.v1
Open publication

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From Genes to Clinical Practice: Exploring the Genomic Underpinnings of Endometrial CancerDOI 10.20944/preprints202410.1326.v1
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