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An Update on the Potential Roles of E2F Family Members in Colorectal Cancer

1 Jul 2021

Abstract excerpt

Colorectal cancer (CRC) is a major health burden worldwide, and thus, optimised diagnosis and treatments are imperative. E2F transcription factors (E2Fs) are a family of transcription factors consisting of eight genes, contributing to the oncogenesis and development of CRC. Importantly, E2Fs control not only the cell cycle but also apoptosis, senescence, DNA damage response, and drug resistance by interacting...

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PMID: 34276228
DOI: 10.2147/cmar.s320193

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