Article
YTHDC1 regulates the postnatal development of heart
2023-09-06
Abstract excerpt
This study aimed to investigate the role of the N6-methyladenosine (m 6 A) reader protein YTHDC1 in heart development and its potential molecular mechanisms. Animal experiments were conducted using cardiac-specific Ythdc1 knockout ( Ythdc1- CKO) mice, and human heart samples were collected from aborted fetuses. Echocardiography, immunoblotting, RNA-Seq, and ATAC-Seq were performed to assess cardiac function, gene...
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Identifiers and source
- Literature Corpus work
- 294aef69-b4a3-51a5-a22f-3aee725f5f42
- DOI
- 10.21203/rs.3.rs-3301770/v1
