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Article

Modeling GATAD1-Associated Dilated Cardiomyopathy in Adult Zebrafish

26 Jan 2016

Abstract excerpt

Animal models have played a critical role in validating human dilated cardiomyopathy (DCM) genes, particularly those that implicate novel mechanisms for heart failure. However, the disease phenotype may be delayed due to age-dependent penetrance. For this reason, we generated an adult zebrafish model, which is a simpler vertebrate model with higher throughput than rodents. Specifically, we studied the zebrafish...

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PMID: 28955713
DOI: 10.3390/jcdd3010006

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