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Single‐Cell Atlas of Neonatal Mouse Hearts Reveals an Unexpected Cardiomyocyte

28 Nov 2023

Abstract excerpt

BACKGROUND: Single-cell RNA sequencing is widely used in cancer research and organ development because of its powerful ability to analyze cellular heterogeneity. However, its application in cardiomyocytes is dissatisfactory mainly because the cardiomyocytes are too large and fragile to withstand traditional single-cell approaches. METHODS AND RESULTS: Through designing the isolation procedure of neonatal mouse...

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PMID: 38014657
DOI: 10.1161/jaha.122.028287

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