Article

HDAC6/FOXP3/HNF4α axis promotes bile acids induced gastric intestinal metaplasia

2021-02-05

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Gastric<bold> </bold>intestinal metaplasia (IM) is an important precancerous lesion. Our previous study has shown that ectopic expression of HDAC6 promotes the activation of intestinal markers in bile acids (BA) induced gastric IM cells; however, the mechanism underlying how HDAC6-mediated epigenetic modifications regulate intestinal markers is not clear.<bold>M...

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Literature Corpus work: 4273564a-93d5-588b-9141-7841e335ee01
DOI: 10.21203/rs.3.rs-155411/v2

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