Article

Clonal phylogeny and evolution of critical cytogenetic aberrations in multiple myeloma at single-cell level by QM-FISH

2021-10-20

Abstract excerpt

Abstract Single-cell analysis is of significant importance in delineating the exact phylogeny of the subclonal population and in discovering subtle diversification. So far, studies of intratumor heterogeneity and clonal evolution in multiple myeloma (MM) were largely focused on the bulk tumor population level. We performed quantitative multigene fluorescence in situ hybridization (QM-FISH) in 129 longitudinal samp...

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Identifiers and source

Literature Corpus work: 29391d43-0a81-5c1f-9caf-85bf76f95607
DOI: 10.1182/bloodadvances.2021004992

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