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Gene co-expression analysis of human <i>RNASEH2A</i> reveals functional networks associated with DNA replication, DNA damage response, and cell cycle regulation

2020-08-27

Abstract excerpt

Ribonuclease H2 (RNase H2) is a key enzyme for the removal of RNA found in DNA-RNA hybrids, playing a fundamental role in biological processes such as DNA replication, telomere maintenance and DNA damage repair. RNase H2 is a trimer composed of three subunits, being RNASEH2A the catalytic subunit. RNASEH2A expression levels have been shown to be upregulated in transformed and cancer cells. In this study we used a...

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Literature Corpus work
290aba84-61bd-5e8a-a145-9ff1ed821c9c
DOI
10.1101/2020.08.27.270595
Open publication

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Gene co-expression analysis of human <i>RNASEH2A</i> reveals functional networks associated with DNA replication, DNA damage response, and cell cycle regulationDOI 10.1101/2020.08.27.270595
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