Article

<i>ARID2</i> deficiency promotes tumor progression and is associated with higher sensitivity to PARP inhibition in lung cancer

2020-01-10

Abstract excerpt

<h4>ABSTRACT</h4> The survival rate in lung cancer remains stubbornly low and there is an urgent need for the identification of new therapeutic targets. Last decade’s research has evidenced a clear role of chromatin structure in cancer development and several members of the SWI/SNF chromatin remodeling complexes have been described altered in different tumor types. Nevertheless, the precise mechanisms of their im...

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Literature Corpus work: 57478c2e-ceed-51c2-b2fc-dca7433b97fd
DOI: 10.1101/2020.01.10.898726

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