Article

Induced pluripotent stem cell-derived astrocytes from patients with schizophrenia exhibit an inflammatory phenotype that affects vascularization

2022-03-08

Abstract excerpt

<h4>Summary</h4> Molecular and functional abnormalities of astrocytes have been implicated in the etiology and pathogenesis of schizophrenia (SCZ). In this study, we examined the proteome, inflammatory responses, and secretome effects on vascularization of human induced pluripotent stem cell (hiPSC)-derived astrocytes from patients with SCZ. Proteomic analysis revealed alterations in proteins related to immune fu...

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Literature Corpus work: 29092797-a8a5-5afe-8a28-db9b4b57522d
DOI: 10.1101/2022.03.07.483024

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