Article

Bcl-2 initiates a new category of oncogenes: regulators of cell death

1992-08-15

Abstract excerpt

PECIFIC CHROMOSOMAL translocations are recur-S rently found in distinct types of ma1ignan~ies.l.~ Indeed, many of these interchromosomal translocations are essentially pathognomonic for a given tumor. The molecular cloning of chromosomal breakpoints has proven a rich source of novel proto-oncogenes. Experimental approaches indicate that deregulation of these genes represents a primary pathogenic event in the gener...

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Literature Corpus work: 28e28311-0c63-516f-930b-d66cdcc96c1f
DOI: 10.1182/blood.v80.4.879.879

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