Article

Clonal hematopoiesis is associated with distinct rheumatoid arthritis phenotypes

2024-10-13

Abstract excerpt

Clonal hematopoiesis (CH) becomes more prevalent with age and may impact the pathophysiology of inflammatory diseases by altering immune cell function. While clonal hematopoiesis of indeterminate potential (CHIP) can promote inflammation in non-malignant conditions, the relationship with rheumatoid arthritis (RA) has not been systematically investigated. We tested whether CHIP mutations are more common in RA using...

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Literature Corpus work: 28c8c714-dc12-5bec-bed7-45418c09e709
DOI: 10.1101/2024.10.10.24315184

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