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Article

Clonal haematopoiesis and risk of incident rheumatoid arthritis: results from the UK Biobank.

Clinical and experimental rheumatology - 1 Jul 2026

Cui Jing, Yu Zhi, Oakes Emily G, Truong Buu, Uddin Mesbah, Bick Alexander, Niroula Abhishek, Solomon Daniel H, Natarajan Pradeep, Costenbader Karen H

Abstract excerpt

OBJECTIVES: Clonal haematopoiesis of indeterminate potential (CH), somatic genetic mutations conferring stem cells selective advantage, are associated with increased inflammatory cytokine production, cardiovascular disease (CVD), and malignancy. We investigated whether CH was related to risk of rheumatoid arthritis (RA), an inflammatory autoimmune disease. METHODS: Within the UK Biobank, we studied 186,577...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41779596
DOI: 10.55563/clinexprheumatol/23hcbl
PMCID: PMC12962563

Genes

SF3B1
TET2
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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