Article

Scaling the Dynamics of Coiled Coils

2026-07-22

Abstract excerpt

Coiled coils are structural motifs in proteins that play diverse functions. In MRE11-RAD50 (MR) complexes, ATP-driven changes in coiled coils are essential for DNA break sensing. However, coiled coil dynamics and its modulation by protein conformational changes remain unclear, partly due to the lack of quantitative tools. Here, we used high-speed atomic force microscopy (HS-AFM) for real-time visualization of the...

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Literature Corpus work: 28910990-49d5-5d53-8397-4bd3d00be020
DOI: 10.64898/2026.07.21.739852

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