Article
Visualization of intrinsically disordered regions of proteins by high-speed atomic force microscopy.
Chemphyschem : a European journal of chemical physics and physical chemistry - 15 Sept 2008
Miyagi Atsushi, Tsunaka Yasuo, Uchihashi Takayuki, Mayanagi Kouta, Hirose Susumu, Morikawa Kosuke, Ando Toshio
Abstract excerpt
Intrinsically disordered (ID) regions of proteins are recognized to be involved in biological processes such as transcription, translation, and cellular signal transduction. Despite the important roles of ID regions, effective methods to observe these thin and flexible structures directly were not available. Herein, we use high-speed atomic force microscopy (AFM) to observe the heterodimeric FACT (facilitates...
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