Article

Detecting global influence of transcription factor interactions on gene expression in lymphoblastoid cells using neural network models

2021-06-20

Abstract excerpt

<h4>Background</h4> Transcription factor(TF) interactions are known to regulate target gene(TG) expression in eukaryotes via TF regulatory modules(TRMs). Such interactions can be formed due to co-localizing TFs binding proximally to each other in the DNA sequence or over long distances between distally binding TFs via chromatin looping. While the former type of interaction has been characterized extensively, long...

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Literature Corpus work: 2878663d-1109-5756-9c86-d2c3d09a1703
DOI: 10.1101/2021.06.18.449031

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