Article

NetREm Network Regression Embeddings reveal cell-type transcription factor coordination for gene regulation

2023-10-30

Abstract excerpt

Transcription factor (TF) coordination plays a key role in target gene (TG) regulation via protein-protein interactions (PPIs) and DNA co-binding to regulatory elements. Single-cell technologies facilitate gene expression measurement for individual cells and cell-type identification, yet the connection between TF coordination and TG regulation of various cell types remains unclear. To address this, we have develop...

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Literature Corpus work: b847860b-9307-5bab-afc6-48cec00f079d
DOI: 10.1101/2023.10.25.563769

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