Article

A Single Cell Perspective on the Effects of Dopamine in the Regulation of HIV Latency Phenotypes in a Myeloid Cell Model

2025-06-11

Abstract excerpt

Psychostimulants such as methamphetamine (Meth) induce high dopamine (DA) levels in the brain, which can modify immune cells expressing DA receptors. This is relevant in conditions of infection with the Human Immunodeficiency Virus (HIV), overlapping with substance use. However, the effects of DA on HIV latency phenotypes are largely unknown. We used single cell methods and gene network computational analysis to u...

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Literature Corpus work: 285f4ca6-0aaa-5644-b2b8-27ce89edab23
DOI: 10.20944/preprints202506.0878.v1

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