Article

Processing of a single ribonucleotide embedded into DNA by human nucleotide excision repair and DNA polymerase η

2019-07-14

Abstract excerpt

<h4>ABSTRACT</h4> DNA polymerases often incorporate non-canonical nucleotide, i.e., ribonucleoside triphosphates into the genomic DNA. Aberrant accumulation of ribonucleotides in the genome causes various cellular abnormalities. Here, we show the possible role of human nucleotide excision repair (NER) and DNA polymerase η (Pol η) in processing of a single ribonucleotide embedded into DNA. We found that the recons...

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Literature Corpus work: 2858a31e-67ab-50b4-8735-9334b9d1b42e
DOI: 10.1101/699587

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