Article

Investigation of transcription factor binding at distal regulatory elements

2018-01-01

Abstract excerpt

Cellular development and function necessitate precise patterns of gene expression. Control of gene expression is in part orchestrated by a class of remote regulatory elements, termed enhancers, which are brought into contact with promoters via DNA looping. Enhancers typically contain clusters of transcription factor binding sites, and TF recruitment to them is thought to play a key role in transcriptional control....

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Literature Corpus work: 284ab7cc-16bb-5fe7-ba34-78b914442f8a
DOI: 10.17863/cam.25144

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