Article

Optimization of parasite DNA enrichment approaches to generate whole genome sequencing data for Plasmodium falciparum from low-parasitaemia samples

2020-03-18

Abstract excerpt

<title>Abstract</title> Background Owing to the large amount of host DNA in clinical samples, generation of high-quality Plasmodium falciparum whole genome sequencing (WGS) data requires enrichment for parasite DNA. Enrichment is often achieved by leukocyte depletion of infected blood prior to storage. However, leukocyte depletion is difficult in low-resource settings and limits analysis to prospectively-colle...

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Literature Corpus work: 2812fac1-95ed-5106-a947-2b8d8a2d7310
DOI: 10.21203/rs.2.17581/v3

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