Article

Engineering Rotating Apical-Out Airway Organoid for Assessing Respiratory Cilia Motility

2022-01-18

Abstract excerpt

Motile cilia project from the airway apical surface and directly interface with inhaled external environment. Due to cilia’s nanoscale dimension and high beating frequency, quantitative assessment of their motility remains a sophisticated task. Here we described a robust approach for reproducible engineering of apical-out airway organoid (AOAO) of defined size. Propelled by exterior-facing cilia beating, the matur...

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Literature Corpus work: 2805559a-ef9c-5b5f-965b-a21f9a10f782
DOI: 10.1101/2022.01.15.476455

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