Cilia dynamics creates a dynamic barrier to penetration of the periciliary layer in human airway epithelia

Abstract excerpt

The ciliated epithelium of the human respiratory tract is covered by the airway surface liquid (ASL), a protective fluid consisting of two layers: the periciliary layer (PCL), where motile cilia reside and generate fluid flow, and an overlying mucus layer. The complex structure and stratified nature of the PCL complicate both the prediction and quantification of fluid flow at the scale of individual or small group...

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• Cystic Fibrosis Research Advances
• Genetic and Kidney Cyst Diseases
• Medical Imaging and Pathology Studies
• Neonatal Respiratory Health Research
• Protist diversity and phylogeny

Identifiers and source

Literature Corpus work

0842d698-7352-57dc-a03c-6d02a959817f

DOI

10.1101/2025.03.21.644548