Article
3D nanoscale architecture of the respiratory epithelium reveals motile cilia-rootlets-mitochondria axis of communication
2024-09-08
Abstract excerpt
A major frontier in single cell biology is decoding how transcriptional states result in cellular-level architectural changes, ultimately driving function. A remarkable example of this cellular remodelling program is the differentiation of airway stem cells into the human respiratory multiciliated epithelium, a tissue barrier protecting against bacteria, viruses and particulate matter. Here, we present the first i...
Topics
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- Cystic Fibrosis Research Advances
- Genetic and Kidney Cyst Diseases
- Medical Imaging and Pathology Studies
- Microfluidic and Bio-sensing Technologies
- Neonatal Respiratory Health Research
- Pulmonary Hypertension Research and Treatments
- Respiratory viral infections research
- Single-cell and spatial transcriptomics
Identifiers and source
- Literature Corpus work
- 5fce463c-3992-5514-a209-4663816c313f
- DOI
- 10.1101/2024.09.08.611854