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Article

Association of Genetic Variants in TPMT, ITPA, NUDT15 With Azathioprine-Induced Myelosuppression in Southwest China Patients With Autoimmune Hepatitis

2020-12-11

Abstract excerpt

<h4>Aims: </h4>: To investigate the influence of TPMT*3C, ITPA, NUDT15 , and 6-thioguanine nucleotides (6-TGN) on AZA-induced myelosuppression in Southwest China AIH patients. <h4>Methods: </h4>: A total of 113 Chinese AIH patients with AZA maintenance treatment were evaluated. Collect the relevant clinical data of patients from the hospital information system. TPMT*3C(rs1142345), ITPA(rs1127354) and NUDT15(rs1168...

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Literature Corpus work
27ec7532-fade-5433-a7c4-fbc31e3c2715
DOI
10.21203/rs.3.rs-123603/v1
Open publication

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Association of Genetic Variants in TPMT, ITPA,&nbsp;NUDT15&nbsp;With&nbsp;Azathioprine-Induced Myelosuppression in Southwest China Patients With Autoimmune HepatitisDOI 10.21203/rs.3.rs-123603/v1
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