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Article

NUDT15 polymorphism explains serious toxicity to azathioprine in Indian patients with chronic immune thrombocytopenia and autoimmune hemolytic anemia: a case series.

Drug metabolism and personalized therapy - 24 Aug 2020

Devasia Anup J, Illangeswaran Raveen Stephen Stallon, Raj Infencia Xavier, George Biju, Balasubramanian Poonkuzhali

Abstract excerpt

OBJECTIVES: Azathioprine (AZA) is a commonly used immunosuppressant in patients with autoimmune diseases. The toxic side effect to AZA (myelosuppression, hair loss, and oral ulcers) are highly unpredictable which can be life threatening if not identified earlier and dose adjustments made or the drug is withdrawn. CASE PRESENTATION: Here we report a case series of five patients with severe toxicity while on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 32827393
DOI: 10.1515/dmpt-2020-0128

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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