Article

Hidden evolutionary constraints dictate the retention of coronavirus accessory genes

2023-10-14

Abstract excerpt

<h4>Summary</h4> Coronaviruses exhibit many mechanisms of genetic innovation, including the acquisition of accessory genes that originate by capture of cellular genes or through duplication of existing viral genes. Accessory genes influence viral host range and cellular tropism, but little is known about how selection acts on these variable regions of virus genomes. We used experimental evolution of mouse hepatit...

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Literature Corpus work: 27c0cc28-8a43-59a1-b83b-c8024fa4916e
DOI: 10.1101/2023.10.12.561935

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