Article

Systematic in vivo interrogation identifies novel enhancers and silencers associated to Atrial Fibrillation

2021-07-14

Abstract excerpt

Cis-regulatory elements control gene expression in time and space and their disruption can lead to pathologies. Reporter assays allow the functional validation of enhancers and other regulatory elements, and such assays by means of the generation of transgenic mice provide a powerful tool to study gene regulation in development and disease. However, these experiments are time-consuming and, thus, their performance...

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Literature Corpus work: 279b755e-aca9-5507-8db5-0ed7d84fa8e2
DOI: 10.1101/2021.07.14.452222

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