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Article

Identification of Functional Variant Enhancers Associated With Atrial Fibrillation

6 Apr 2020

Abstract excerpt

Rationale: Genome-wide association studies have identified a large number of common variants (single-nucleotide polymorphisms) associated with atrial fibrillation (AF). These variants are located mainly in noncoding regions of the genome and likely include variants that modulate the function of transcriptional regulatory elements (REs) such as enhancers. However, the actual REs modulated by variants and the...

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Share to Atrial Fibrillation Management and Outcomes
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PMID: 32248749
DOI: 10.1161/circresaha.119.316006

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