Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function

Abstract excerpt

Eph receptor tyrosine kinases participate in a variety of normal and pathogenic processes during development and throughout adulthood. This versatility is likely facilitated by the ability of Eph receptors to signal through diverse cellular signalling pathways: primarily by controlling cytoskeletal dynamics, but also by regulating cellular growth, proliferation, and survival. Despite many proteins linked to these...

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• Autophagy in Disease and Therapy
• Caenorhabditis elegans
• Caenorhabditis elegans Proteins
• Cell Communication
• Genetics and Neurodevelopmental Disorders
• Peptidase Inhibition and Analysis
• Protein Degradation and Inhibitors
• Ubiquitin and proteasome pathways

Identifiers and source

Literature Corpus work

27512466-057d-5c78-9114-476d65800fcf

DOI

10.1101/2023.06.12.544638