Article

High-Throughput IgG Epitope Mapping of Tetanus Neurotoxin: Implications for Immunotherapy and Vaccine Design

2023-02-20

Abstract excerpt

<h4>Background: </h4> Tetanus is an acute, fatal disease caused by exotoxins released from Clostridium tetani during infections. A protective humoral immune response can be induced by vaccinations with pediatric and booster combinatorial vaccines that contain inactivated tetanus neurotoxin (TeNT) as a major antigen. Although some epitopes in NeNT have been described using various ap-proaches, a comprehensive list...

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Literature Corpus work: 27436508-cd51-5b9f-a16a-faaf4f2581d6
DOI: 10.20944/preprints202302.0332.v1

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