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High Throughput T Epitope Mapping and Vaccine Development

1 Jan 2010

Abstract excerpt

Mapping of antigenic peptide sequences from proteins of relevant pathogens recognized by T helper (Th) and by cytolytic T lymphocytes (CTL) is crucial for vaccine development. In fact, mapping of T-cell epitopes provides useful information for the design of peptide-based vaccines and of peptide libraries to monitor specific cellular immunity in protected individuals, patients and vaccinees. Nevertheless, epitope...

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PMID: 20617148
DOI: 10.1155/2010/325720

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