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Article

A Novel High-Potency Tetanus Vaccine.

mBio - 11 Aug 2020

Przedpelski Amanda, Tepp William H, Pellett Sabine, Johnson Eric A, Barbieri Joseph T

Abstract excerpt

Chemically inactivated tetanus toxoid (CITT) is clinically effective and widely used. However, CITT is a crude nonmalleable vaccine that contains hundreds of Clostridium tetani proteins, and the active component is present in variable and sometimes minor percentages of vaccine mass. Recombinant production of a genetically inactivated tetanus vaccine offers an opportunity to replace and improve the current tetanus...

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Source

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Identifiers

PMID: 32788381
DOI: 10.1128/mBio.01668-20
PMCID: PMC7439469

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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