Article

Characterization of quiescent subpopulations and proliferative compartments in glioblastoma

2025-10-06

Abstract excerpt

Glioblastoma (GBM) quiescent (Q) cell populations are hypothesized to contain cancer stem-like cells (CSC) that drive tumor growth, cellular heterogeneity, and recurrence. However, GBM tumors do not neatly resolve into developmental hierarchies and Q stem-like activities are difficult to assess. Here, we evaluated tumor Q subpopulations in patient-derived GBM xenograft tumors using live cell reporters, DNA label r...

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Literature Corpus work: 27206813-1fe5-5531-81ca-58f94bc9ca40
DOI: 10.1101/2025.10.03.680278

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