Article
mSignatureDB: a database for deciphering mutational signatures in human cancers.
Nucleic acids research - 4 Jan 2018
Huang Po-Jung, Chiu Ling-Ya, Lee Chi-Ching, Yeh Yuan-Ming, Huang Kuo-Yang, Chiu Cheng-Hsun, Tang Petrus
Abstract excerpt
Cancer is a genetic disease caused by somatic mutations; however, the understanding of the causative biological processes generating these mutations is limited. A cancer genome bears the cumulative effects of mutational processes during tumor development. Deciphering mutational signatures in cancer is a new topic in cancer research. The Wellcome Trust Sanger Institute (WTSI) has categorized 30 reference...
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