Article

Genetic variations in<i>EIF2AK3</i>are associated with neurocognitive impairment in people living with HIV

2022-04-23

Abstract excerpt

Coding and noncoding single-nucleotide variants (SNVs) of EIF2AK3 , which encodes an integrated stress response (ISR) kinase, may play a role in neurodegenerative disorders. We used a candidate gene approach to determine the correlation of EIF2AK3 SNVs with neurocognitive (NC) impairment (NCI), which can persist with viral suppression from antiretroviral therapy (ART) in people with HIV (PWH). This retrospective s...

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Literature Corpus work: 26fb9518-f21d-5213-8b61-c94da0cf9d69
DOI: 10.1101/2022.04.20.22273997

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