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Article

Association of apolipoprotein E epsilon 4 and cognitive impairment in adults living with human immunodeficiency virus: a meta-analysis.

Chinese medical journal - 20 Nov 2022

Mu Tingting, Wei Jiaqi, Sun Jun, Jin Junyan, Zhang Tong, Wu Hao, Su Bin

Abstract excerpt

BACKGROUND: It is controversial whether the apolipoprotein E epsilon 4 allele (APOE ε4) is a risk gene for human immunodeficiency virus (HIV)-related neurocognitive impairment. This meta-analysis aimed to summarize evidence of the associations between APOE ε4 and cognitive impairment in people living with HIV (PLWH). METHODS: Our study conducted a systematic literature search of PubMed, Web of Science, Embase,...

Topics

Male
Female
Humans
Adult
Adolescent
Apolipoprotein E4
HIV
Cognitive Dysfunction
Genotype
Neuropsychological Tests
HIV Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Apolipoproteins E

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Open in PubMed Open full text

Identifiers

PMID: 36719356
DOI: 10.1097/CM9.0000000000002480
PMCID: PMC9945176

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-36719356-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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