Genome-wide association study of HIV-associated neurocognitive disorder (HAND): A CHARTER group study.

doi:10.1002/ajmg.b.32530

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Article

Genome-wide association study of HIV-associated neurocognitive disorder (HAND): A CHARTER group study.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jun 2017

Jia Peilin, Zhao Zhongming, Hulgan Todd, Bush William S, Samuels David C, Bloss Cinnamon S, Heaton Robert K, Ellis Ronald J, Schork Nicholas, Marra Christina M, Collier Ann C, Clifford David B, Gelman Benjamin B, Sacktor Ned, Morgello Susan, Simpson David M, McCutchan J Allen, Barnholtz-Sloan Jill S, Franklin Donald R, Rosario Debralee, Letendre Scott L, Grant Igor, Kallianpur Asha R

Abstract excerpt

HIV-associated neurocognitive disorder (HAND) often complicates HIV infection despite combination antiretroviral therapy (ART) and may be influenced by host genomics. We performed a genome-wide association study (GWAS) of HAND in 1,050 CNS HIV Anti-Retroviral Therapy Effects Research (CHARTER) Study participants. All participants underwent standardized, comprehensive neurocognitive, and neuromedical assessments...

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PMID: 28447399
DOI: 10.1002/ajmg.b.32530
PMCID: PMC5435520

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SH3RF3

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