Article

A machine learning approach to define antimalarial drug action from heterogeneous cell-based screens

2019-12-20

Abstract excerpt

Drug resistance threatens the effective prevention and treatment of an ever-increasing range of human infections. This highlights an urgent need for new and improved drugs with novel mechanisms of action to avoid cross-resistance. Current cell-based drug screens are, however, restricted to binary live/dead readouts with no provision for mechanism of action prediction. Machine learning methods are increasingly bein...

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Literature Corpus work: 26fa5508-b1f3-5311-a72e-d1d269c96e1d
DOI: 10.1101/2019.12.19.882480

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